The Relationship Between Long-Term Sleep Problems and Alzheimer's Risk

Serdar HocamAuthor & Editor

Experts state that long-term sleep disturbances may be linked to cognitive decline and the risk of Alzheimer's, but are not considered a definitive cause on their own.

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Uzun süreli uyku sorunları Alzheimer riskiyle ilişkili olabilir

Assoc. Prof. Dr. Demet Aygün Üstel, a Neurology Specialist at Biruni University Medical Faculty Hospital, stated that long-standing sleep problems may be associated with cognitive decline and the risk of Alzheimer's disease.

The Importance of Sleep for the Brain

It was stated that sleep is not merely a resting process, but that during sleep, the brain continues its activities related to memory, learning, and the removal of metabolic waste.

Two-Way Sleep Relationship

It was noted that the relationship between sleep and Alzheimer's disease can be bidirectional, meaning sleep disorders can constitute a risk factor while changes in the brain can also disrupt sleep patterns.

Conditions for Quality Sleep

It was emphasized that frequent waking up during the night and a decrease in deep sleep periods negatively affect sleep quality, and that even if one stays in bed for eight hours, fragmentations prevent adequate rest.

Symptoms of Sleep Apnea

It was recommended that an evaluation for sleep apnea be conducted in cases of loud snoring, noticing breathing cessation during sleep, waking up unrefreshed in the morning, and excessive daytime sleepiness.

Metabolic Wastes and Proteins

It was reported that the mechanisms in the brain that clear metabolic waste work actively during sleep, and the relationship between sleep and beta-amyloid and tau proteins, which play a role in Alzheimer's, is being investigated.

Call for Early Evaluation

It was stated that medical evaluation should not be delayed when experiencing recent memory loss, repeatedly asking the same questions, difficulty with daily tasks, and pronounced sleep disturbances.